I believe using either of these two applications should not pose any problems for implementing your spreadsheet automation ideas. This is because both have always been "friendly", towards making it easy for users to get more functionality out of them by way of custom programming.
From this point on, I will refer to only one of the above mentioned applications, because it is my preferred work environment. That is Microsoft Excel. I believe users of other spreadsheet applications will be able to adapt whatever I say from here for use in their own peculiar environments.
I am keen to encourage individuals and organisations to explore using advanced MS Excel formulas and functions, in conjunction with Excel VBA programming, to develop customised spreadsheet applications that will solve typical problems end_users encounter daily in trying to record/analyse data and generate reports.
VBA is therefore different from the Standalone Visual Basic program used(by professional programmers) for developing commercial quality software applications _ though it borrows many of the latter's features. Think of Excel VBA as being the standalone Visual Basic software, built into Excel for the benefit of Excel users who are not necessarily programmers, but who are keen to exert more control over the application. So, Excel VB offers any interested users the necessary tools to make the application deliver more functionality. The final product is still an Excel document, but with extra functionalities added using VBA.