Custom spreadsheet solutions which survive long after the developer has "left the scene", are often those which users accept because they discover it _ among other benefits _ makes their work quicker and easier to do. That is why the best person to develop such solutions tend to be one who works in that area, and is therefore familiar with the way the manual system operates. S/he would have an "insider's" perspective of the best way to introduce automation other users will readily adopt _ even as it solves the identified problem(s).
I believe using either of these two applications should not pose any problems for implementing your spreadsheet automation ideas. This is because both have always been "friendly", towards making it easy for users to get more functionality out of them by way of custom programming.
At times, they would prefer to click a button that says "Print ABC", or "Print XYZ" report, instead of having to crawl all over the huge spreadsheet(and get "lost" every now and then), to highlight and print different report pages. Using a custom built data entry form to make data entries into 14 different cells in different parts of a table(at the same time/with one click) would, for them, be "heaven" compared to making the entries one at a time.
To elaborate further: A one_page Variable Costs Analysis report sheet automatically generated by the custom spreadsheet application I earlier described, was a powerful tool used by top management to quickly assess performances of individual breweries. Among other benefits, the report made it quite easy to realistically compare sister breweries in different locations(even across countries) based on common denominators. Apart from summarising brewing/packaging materials in two groups _